Synthetic organic

AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ.A PI3K inhibitor and antiplatelet agent.

AZD6495.

AZD6495.

AZD6538.

AZD6538.

AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.

AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.

AZD6703.

AZD6703.

AZD7268.

AZD7268.

InformationAZD7545 AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 , respectively. It failed to inhibit PDHK4 at higher concentrations(&gt:10 nM), AZD7545 stimulates PDHK4 activity.TargetsPDHK2 : PDHK1 6.4 nM: