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C336172-1mgCdk1/5 Inhibitor is a 3-amino substituted pyrazoloquinoxaline compound that acts as a selective inhibitor of Cdk1 and Cdk5 (IC|50|= 600 nM for Cdk1/cyclin B and 400 nM for Cdk5/p25. Cdk1/5 Inhibitor is also shown to inhibit GSK-3β with (IC|50|>:
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C336172-5mgCdk1/5 Inhibitor is a 3-amino substituted pyrazoloquinoxaline compound that acts as a selective inhibitor of Cdk1 and Cdk5 (IC|50|= 600 nM for Cdk1/cyclin B and 400 nM for Cdk5/p25. Cdk1/5 Inhibitor is also shown to inhibit GSK-3β with (IC|50|>:
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C608435-25mgCDK12 inhibitor 2.
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C608435-5mgCDK12 inhibitor 2.
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C336666-1mgCdk4 Inhibitor is a cell-permeable, unsymmetrical indolocarbazole compound that displays antiproliferative properties. Acts as a potent, selective, and ATP-competitive inhibitor of Cdk4/cyclin D1 (IC|50|= 76 nM). It inhibits the activity of other
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C413829-100mgInformationCDKI-73 (LS-007) is a potentCDKinhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly
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C413829-10mgInformationCDKI-73 (LS-007) is a potentCDKinhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly
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C413829-25mgInformationCDKI-73 (LS-007) is a potentCDKinhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly
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C413829-50mgInformationCDKI-73 (LS-007) is a potentCDKinhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly
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C413829-5mgInformationCDKI-73 (LS-007) is a potentCDKinhibitor in vitro with IC50 of 8.17 nM, 3.27 nM, 8.18 nM, and 5.78 nM for CDK1, CDK2, CDK4, and CDK9, respectively. CDKI-73 induces apoptosis in cancer cells. CDKI-73 is an orally bioavailable and highly
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C341174-10mgCDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC|50|= 12 nM). This compound competitively inhibits all PDE4 isoenzymes, which in turn prevents the cleavage of phosphodiester bonds found in secondary
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C341174-50mgCDP 840 hydrochloride is a potent and selective inhibitor of phosphodiesterase 4 (PDE4) (IC|50|= 12 nM). This compound competitively inhibits all PDE4 isoenzymes, which in turn prevents the cleavage of phosphodiester bonds found in secondary