Synthetic organic

InformationJNJ-38877618(OMO-1) JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable Met (c-Met) kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant Met (c-Met) (2 and 3

JNJ-39319202.

JNJ-39319202.

JNJ-40068782.

JNJ-40068782.

InformationJNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

InformationJNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

InformationJNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

InformationJNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.

InformationJNJ-42153605 JNJ-42153605 is a potent and selective mGlu2 receptor positive allosteric modulator with an EC50 of 17 nM.TargetsmGlu2 receptor 17 nM(EC50)In vitroJNJ-42153605 is found to not have agonist or antagonist activity toward other

InformationJNJ-42153605 JNJ-42153605 is a potent and selective mGlu2 receptor positive allosteric modulator with an EC50 of 17 nM.TargetsmGlu2 receptor 17 nM(EC50)In vitroJNJ-42153605 is found to not have agonist or antagonist activity toward other

InformationJNJ-42153605 JNJ-42153605 is a potent and selective mGlu2 receptor positive allosteric modulator with an EC50 of 17 nM.TargetsmGlu2 receptor 17 nM(EC50)In vitroJNJ-42153605 is found to not have agonist or antagonist activity toward other