Synthetic organic

Ko 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM), Ko 143 displays &gt: 200-fold selectivity over P-gp and MRP-1 transporters.A selective BCRP multidrug transporter inhibitor.

Ko 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM), Ko 143 displays &gt: 200-fold selectivity over P-gp and MRP-1 transporters.A selective BCRP multidrug transporter inhibitor.

Ko 143 is a potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM), Ko 143 displays &gt: 200-fold selectivity over P-gp and MRP-1 transporters.A selective BCRP multidrug transporter inhibitor.

InformationKO-947 KO-947 is a potent and selective inhibitor of ERK1/2 kinases . KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations.TargetsERK.

InformationKO-947 KO-947 is a potent and selective inhibitor of ERK1/2 kinases . KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling at low nanomolar concentrations.TargetsERK.

KOS1326.

KOS1326.

KPR-5714.

KPR-5714.

Product description：Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.

Product description：Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.

Product description：Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.