Synthetic organic

InformationLDC1267 LDC1267 is a highly selective TAM kinase inhibitor with IC50 of &lt:5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.TargetsMer (Cell-free assay): Tyro3

InformationLDC1267 LDC1267 is a highly selective TAM kinase inhibitor with IC50 of &lt:5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.TargetsMer (Cell-free assay): Tyro3

InformationLDC1267 LDC1267 is a highly selective TAM kinase inhibitor with IC50 of &lt:5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.TargetsMer (Cell-free assay): Tyro3

InformationLDC1267 LDC1267 is a highly selective TAM kinase inhibitor with IC50 of &lt:5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.TargetsMer (Cell-free assay): Tyro3

Potent and selective ALK2 inhibitor.

Potent and selective ALK2 inhibitor.

Potent and selective ALK2 inhibitor.

Potent and selective ALK2 inhibitor.

Potent and selective ALK2 inhibitor.

Potent and selective ALK2 inhibitor.

Application：LE 135 has been used for in vitro islet treatment.

Application：LE 135 has been used for in vitro islet treatment.