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rp173943-500μgectodysplasin A1
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G656495-1mlGSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC 50 s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses
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H651488-100mgHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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H651488-10mgHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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H651488-25mgHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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H651488-50mgHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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H651488-5mgHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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H656696-1mlHS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a K i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2 , MAP4K5, IRAK1 , NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC 50 values of 8.25, 29, 33, 63,
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I649948-1mgISIS?104838?is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha) ,?a substance that contributes to joint pain and swelling in rheumatoid arthritis.Form:Solid
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I649948-5mgISIS?104838?is an antisense oligonucleotide agent that reduces the production of tumor necrosis factor (TNF-alpha) ,?a substance that contributes to joint pain and swelling in rheumatoid arthritis.Form:Solid
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I649196-10mgIW927 is a potent small molecule antagonist that blocks the binding of TNF-α to TNFRc1 with an IC 50 value of 50 nM and disrupts TNFα-induced IκB phosphorylation with an IC 50 value of 600 nM.Form:Solid
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I649196-25mgIW927 is a potent small molecule antagonist that blocks the binding of TNF-α to TNFRc1 with an IC 50 value of 50 nM and disrupts TNFα-induced IκB phosphorylation with an IC 50 value of 600 nM.Form:Solid