Wnt family ligands

ASN007 (ERK-IN-3) benzenesulfonate is a potent and orally active inhibitor of ERK . ASN007 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ASN007 benzenesulfonate can be used for the research of cancers driven by RAS

ASN007 (ERK-IN-3) benzenesulfonate is a potent and orally active inhibitor of ERK . ASN007 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ASN007 benzenesulfonate can be used for the research of cancers driven by RAS

ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and

ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.In VitroThe inhibition of AKT2 by AT7867 is shown to be ATP-competitive with a K i of

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.In VitroThe inhibition of AKT2 by AT7867 is shown to be ATP-competitive with a K i of

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.In VitroThe inhibition of AKT2 by AT7867 is shown to be ATP-competitive with a K i of

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.In VitroThe inhibition of AKT2 by AT7867 is shown to be ATP-competitive with a K i of

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively.In VitroThe inhibition of AKT2 by AT7867 is shown to be ATP-competitive with a K i of

Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42 . Aβ42-IN-2 can be used for the research of Alzheimer's diseaseForm:SolidIC50&amp Target:Αβ 42

Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42 . Aβ42-IN-2 can be used for the research of Alzheimer's diseaseForm:SolidIC50&amp Target:Αβ 42

Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42 . Aβ42-IN-2 can be used for the research of Alzheimer's diseaseForm:SolidIC50&amp Target:Αβ 42