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D649090-1mgDS89002333 is an orally active and potent PRKACA inhibitor, with an IC 50 of 0.3 nM. DS89002333 shows good anti-tumor activity in an FL-HCC patient-derived xenograft model (expressing the DNAJB1-PRKACA fusion gene). DS89002333 can be used in study
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D649090-5mgDS89002333 is an orally active and potent PRKACA inhibitor, with an IC 50 of 0.3 nM. DS89002333 shows good anti-tumor activity in an FL-HCC patient-derived xenograft model (expressing the DNAJB1-PRKACA fusion gene). DS89002333 can be used in study
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E647756-100mgELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is
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E647756-10mgELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is
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E647756-50mgELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is
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E647756-5mgELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12 nM and 656 nM for PS1 and PS2, respectively. ELN318463 is
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E650811-10mgELN318463 racemate is the racemate of ELN318463. ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12nM and 656
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E650811-20mgELN318463 racemate is the racemate of ELN318463. ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12nM and 656
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E650811-5mgELN318463 racemate is the racemate of ELN318463. ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor. ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC 50 s of 12nM and 656
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E649856-10mgEMT inhibitor-1 is an inhibitor of of Hippo , TGF-β , and Wnt signaling pathways with antitumor activities.In VitroEMT inhibitor-1 (C19) (0-10μM 24 hours) is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities,
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E649856-25mgEMT inhibitor-1 is an inhibitor of of Hippo , TGF-β , and Wnt signaling pathways with antitumor activities.In VitroEMT inhibitor-1 (C19) (0-10μM 24 hours) is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities,
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E649856-5mgEMT inhibitor-1 is an inhibitor of of Hippo , TGF-β , and Wnt signaling pathways with antitumor activities.In VitroEMT inhibitor-1 (C19) (0-10μM 24 hours) is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities,