Wnt family ligands

(rel)-AR234960 is an active relative configuration of AR234960. AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac

(rel)-AR234960 is an active relative configuration of AR234960. AR234960, a non-peptide MAS (a G protein-coupled receptor) agonist, increases both mRNA and protein levels of CTGF via ERK1/2 signaling in HEK293-MAS cells and adult human cardiac

10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.Form:Solid

10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity.Form:Solid

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectivelyForm:SolidIC50&amp Target:GSK-3β 9 nM (IC 50 )

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectivelyForm:SolidIC50&amp Target:GSK-3β 9 nM (IC 50 )

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectivelyForm:SolidIC50&amp Target:GSK-3β 9 nM (IC 50 )

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectivelyForm:SolidIC50&amp Target:GSK-3β 9 nM (IC 50 )

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β , CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC 50 s of 9, 20 and 25 nM, respectivelyIC50&amp Target:GSK-3β 9 nM (IC 50 ) Cdk5/p25

7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migrationIC50&amp Target:STAT3

7-epi-Isogarcinol is a polycyclic polyprenylated acylphloroglucinol (PPAP), with moderate antiproliferative activity. 7-epi-Isogarcinol blocks STAT3 signaling pathway, to induce apoptosis and inhibit cell migrationIC50&amp Target:STAT3

8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity.In Vitro8-Chloro-cAMP markedly inhibits vascular smooth muscle cell (VSMC) proliferation in vitro, reduces