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E646241-10mg8-Epixanthatin is a potential colchicine binding site inhibitor isolated from Xanthium chinese Mill. 8-Epixanthatin can inhibit the activation of STAT3 , induce apoptosis , and has anti-tumor activity.In Vitro8-Epixanthatin(2-20 μM, 12 h) inhibits
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E646241-5mg8-Epixanthatin is a potential colchicine binding site inhibitor isolated from Xanthium chinese Mill. 8-Epixanthatin can inhibit the activation of STAT3 , induce apoptosis , and has anti-tumor activity.In Vitro8-Epixanthatin(2-20 μM, 12 h) inhibits
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P651550-100μg8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by
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A649618-100mgABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A649618-10mgABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A649618-25mgABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A649618-50mgABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A649618-5mgABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A655927-1mlABC1183 is an orally active selective dual GSK3 and CDK9 inhibitor. ABC1183 inhibits GSK3β, GSK3α and CDK9/cyclin T1 with the IC 50 values of 657 nM, 327 nM and 321 nM, respectively. ABC1183 has anti-inflammatory and anti-tumor activitiesIn
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A650196-10mgABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM ( IC 50 =13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUMIn VitroABC99 (0.1~10 μΜ 2 hours SW620 cells) inhibits NOTUM in a
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A650196-1mgABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM ( IC 50 =13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUMIn VitroABC99 (0.1~10 μΜ 2 hours SW620 cells) inhibits NOTUM in a
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A650196-5mgABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM ( IC 50 =13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUMIn VitroABC99 (0.1~10 μΜ 2 hours SW620 cells) inhibits NOTUM in a