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M648664-1mgMongersen (GED-0301) is a specific and orally active SMAD7 antisense oligonucleotide. Mongersen restores TGF-β1 activity leading to inhibition of inflammatory signals. Mongersen can attenuate Crohn's disease-like experimental colitis in mice.In
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M648577-100mgMRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling.Form:Solid
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M648577-10mgMRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling.Form:Solid
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M648577-50mgMRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling.Form:Solid
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M648577-5mgMRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling.Form:Solid
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M651947-10mgMRT-81 is a potent antagonist of human and rodent smoothened ( Smo ) receptors, with an IC 50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancerIn VitroMRT-81
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M651947-25mgMRT-81 is a potent antagonist of human and rodent smoothened ( Smo ) receptors, with an IC 50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancerIn VitroMRT-81
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M651947-50mgMRT-81 is a potent antagonist of human and rodent smoothened ( Smo ) receptors, with an IC 50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancerIn VitroMRT-81
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M651947-5mgMRT-81 is a potent antagonist of human and rodent smoothened ( Smo ) receptors, with an IC 50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancerIn VitroMRT-81
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M656891-1mlMRT-81 is a potent antagonist of human and rodent smoothened ( Smo ) receptors, with an IC 50 value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 can be used for the research of cancerIn VitroMRT-81
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M646192-100mgMRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat
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M646192-10mgMRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat