Wnt family ligands

MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat

MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat

MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat

MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat

MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling.In VitroMRT-83 displays full antagonist properties with an IC 50 (~3 nM) for inhibiting ShhN (3 nM)-induced proliferation of rat

MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo . MRT-83 (hydrochloride) has the potential for

MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo . MRT-83 (hydrochloride) has the potential for

MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo . MRT-83 (hydrochloride) has the potential for

MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo . MRT-83 (hydrochloride) has the potential for

MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo . MRT-83 (hydrochloride) has the potential for

MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 ( IC 50 =0.9 µM for CK1δ) and CHK1 ( IC 50 =0.23 µM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisationIn VitroMRT00033659 (5-40 µM 48

MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 ( IC 50 =0.9 µM for CK1δ) and CHK1 ( IC 50 =0.23 µM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisationIn VitroMRT00033659 (5-40 µM 48