Wnt family ligands

Notch 1 TFA (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of

Notch inhibitor 1 is a potent Notch inhibitor, with IC 50 s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancerIn VitroNotch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway. MCE has not

Notch inhibitor 1 is a potent Notch inhibitor, with IC 50 s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancerIn VitroNotch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway. MCE has not

NRX-103095 is an enhancer of the interaction between β-catenin , and its cognate E3 ligase , SCF β-TrCP . NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC 50 of 163 nMForm:SolidIC50&amp Target:EC50: 163 nM

NRX-103095 is an enhancer of the interaction between β-catenin , and its cognate E3 ligase , SCF β-TrCP . NRX-103095 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC 50 of 163 nMForm:SolidIC50&amp Target:EC50: 163 nM

NRX-2663 is an enhancer of the interaction between β-catenin , and its cognate E3 ligase , SCF β-TrCP . NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC 50 of 22.9 µM and a K d of 54.8 nMIn VitroNRX-2663 displays both

NRX-2663 is an enhancer of the interaction between β-catenin , and its cognate E3 ligase , SCF β-TrCP . NRX-2663 enhances the binding of β-catenin peptide for β-TrCP with an EC 50 of 22.9 µM and a K d of 54.8 nMIn VitroNRX-2663 displays both

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 ( TET1 ) and 5-hydroxymethylcytosine ( 5hmC ). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5In VitroNSC-370284 (0-500 nM 24 h or 48 h) inhibits

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 ( TET1 ) and 5-hydroxymethylcytosine ( 5hmC ). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5In VitroNSC-370284 (0-500 nM 24 h or 48 h) inhibits

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 ( TET1 ) and 5-hydroxymethylcytosine ( 5hmC ). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5In VitroNSC-370284 (0-500 nM 24 h or 48 h) inhibits

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 ( TET1 ) and 5-hydroxymethylcytosine ( 5hmC ). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5In VitroNSC-370284 (0-500 nM 24 h or 48 h) inhibits

NSC-370284 is a selective inhibitor of ten-eleven translocation 1 ( TET1 ) and 5-hydroxymethylcytosine ( 5hmC ). NSC-370284 significantly inhibits the level of TET1 expression via targets STAT3/5In VitroNSC-370284 (0-500 nM 24 h or 48 h) inhibits