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R651307-10mgRavoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC 50 of 6.1 nM and 3.1 nM for ERK1 and ERK2 , respectively.In VitroRavoxertinib also inhibits p90RSK with IC 50 of 12 nM.
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R651307-2mgRavoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC 50 of 6.1 nM and 3.1 nM for ERK1 and ERK2 , respectively.In VitroRavoxertinib also inhibits p90RSK with IC 50 of 12 nM.
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R651307-50mgRavoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC 50 of 6.1 nM and 3.1 nM for ERK1 and ERK2 , respectively.In VitroRavoxertinib also inhibits p90RSK with IC 50 of 12 nM.
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R651307-5mgRavoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC 50 of 6.1 nM and 3.1 nM for ERK1 and ERK2 , respectively.In VitroRavoxertinib also inhibits p90RSK with IC 50 of 12 nM.
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R656619-1mlRavoxertinib hydrochloride (GDC-0994 hydrochloride) is an orally bioavailable inhibitor selective for ERK kinase activity with IC 50 of 6.1 nM and 3.1 nM for ERK1 and ERK2 , respectively.In VitroRavoxertinib also inhibits p90RSK with IC 50 of 12 nM.
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R661713-1mlRBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation.In Vitro:RIN1 inhibits the proliferation of hematologic cancer cell
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R647293-100mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases
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R647293-10mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases
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R647293-1mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases
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R647293-25mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases
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R647293-50mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases
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R647293-5mgRho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor ( K i values of 30.5 and 3.9 nM for ROCK1 and ROCK2 , respectively) extracted from US20090325960A1, compound 1.008In VitroRho-Kinase-IN-1 is a ROCK inhibitor which can be useful for treating diseases