Wnt family ligands

SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine ( HY-17024 ) inhibition of Smo .Appearance:SolidIC50&amp

SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine ( HY-17024 ) inhibition of Smo .IC50&amp Target:EC50: 3 nM

SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).Appearance:SolidBiological Activity:SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).

SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).Appearance:SolidBiological Activity:SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).

SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).Appearance:SolidBiological Activity:SAG-d 3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM Kd=59 nM).

Saikosaponin B1 is a bioactive constituent of Radix Bupleuri with anticancer activity. Saikosaponin B1 significantly inhibits tumor growth in Medulloblastoma (MB) model by inhibiting the Hedgehog pathway through targeting SMO.Form:Solid

Saikosaponin B1 is a bioactive constituent of Radix Bupleuri with anticancer activity. Saikosaponin B1 significantly inhibits tumor growth in Medulloblastoma (MB) model by inhibiting the Hedgehog pathway through targeting SMO.Form:Solid

Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells.In

Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells.In

SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. SAR407899 shows stable inhibition of migrasome formation.In

SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. SAR407899 shows stable inhibition of migrasome formation.In

SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. SAR407899 shows stable inhibition of migrasome formation.In