Wnt family ligands

Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family membersIn VitroStafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other

Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family membersIn VitroStafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other

Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family membersIn VitroStafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other

Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family membersIn VitroStafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other

Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family membersIn VitroStafia-1 shows at least 9-fold selectivity over STAT5b and higher selectivity against other

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5bIn VitroStafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5bIn VitroStafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5bIn VitroStafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression

Stafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression significantly, and has no obvious inhibition on pSTAT5bIn VitroStafia-1-dipivaloyloxymethyl ester (compound 27, 0-200 μM) decreases pSTAT5a expression

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nMIn VitroStafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a. MCE has

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nMIn VitroStafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a. MCE has

Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nMIn VitroStafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a. MCE has