General description
Phenol-petroleum ether extracted lipopolysaccharide (LPS) containing ≤0.3% proteins. LPS 595 (Re) has been shown to stimulate Toll-like receptor-4 (TLR4), but not TLR2, signaling in human cell lines.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Stimulate Toll-like receptor-4 (TLR4) signaling in human cell lines
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Preparation Note
Warming to 37°C with intermittent vortexing or sonication may be required to achieve complete solubilization in H₂O.
Reconstitution
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months.
Other Notes
Hirschfeld, M., et al. 2000. J. Immunol.165, 618.
Tapping, R.I., et al. 2000. J. Immunol.165, 5780.
Galanos, C., et al. 1969. Eur. J. Biochem.9, 245.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Quality Level: 100. form: lyophilized. manufacturer/tradename: Calbiochem®. . storage condition: OK to freeze. solubility: 0.5% triethylamine: 1 . mg/mL, water: 1 . mg/mL. shipped in: ambient. storage temp.: 2-8°C. Pictograms: GHS06. Signal Word: Danger. Hazard Statements: H300. Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501. Hazard Classifications: Acute Tox. 2 Oral. Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 41202056
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 437628-1MG
