LOMERIZINE DIHYDROCHLORIDE (C005B-456066)

Catalog No.: C005B-456066
Mfr. No.: L6295-10MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 10
UOM: MG

Price: $246.41

List Price: $273.79

Biochem/physiol Actions Lomerizine dihydrochloride is a voltage-dependent calcium channel blocker and selective cerebral vasodilator. It is one of the most selective calcium channel blockers for the CNS and cerebral arteries.

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Description
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Biochem/physiol Actions

Lomerizine dihydrochloride is a voltage-dependent calcium channel blocker and selective cerebral vasodilator. It is one of the most selective calcium channel blockers for the CNS and cerebral arteries. It has been reported to inhibit both T-type and L-type Ca2+ currents in rat hippocampal CA1 pyramidal neurons, to prevent glutamate-induced neurotoxicity in rat hippocampal primary cell cultures, and to exhibit protective effects in animal models of migraine, ischemia and hypoxia. In Japan, lomerizine has been used as the first-line prophylactic drug for migraines.

UPC:: 51143215
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: L6295-10MG
CAS:: 101477-54-7

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