General description
Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO).
Application
LOPAC®1280 has been used:
- in the screening of novel inhibitors for chemotaxis/ migration using Dictyostelium as a model
- to test the ability to modulate and to measure forskolin-stimulated cAMP levels in CHO-hCB2 cells and to modulate ligand-induced receptor/β-arrestin interaction
- in screening of small molecules for activating bone morphogenetic protein (BMP) signaling
- in screening of compounds that plays a role in regulating subcellular localization of nitric oxide associated protein 1 (NOA1) protein
Features and Benefits
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:
- Apoptosis
- G Proteins & Cyclic Nucleotides
- Gene Regulation & Expression
- Ion Channels
- Lipid Signaling
- Multi-Drug Resistance
- Neurotransmission
- Phosphorylation
SDFile provided to construct a database containing:
- Structure
- Primary Name
- Secondary Name
- Pharmacological Activity
- Product Number
- Rack Position
Collection of 1,280 Pharmacologically-Active Sigma Compounds
To request a list of components, please visit sigma.com/LOPAC
Other Notes
For sale in the U.S. only. Customers outside of the U.S. should refer to product code LO3300.
Legal Information
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
Shipping Information:
Hazmat Fee: $65.00 + applicable shipping charges are added after the order is placed.
Dry Ice Surcharge & Ice Pack Shipments: $40
More Information: https://cenmed.com/shipping-returns
- UPC:
- 51171524
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- LO1280-1KT
- Temperature Control Device:
- Yes
