LP44 (C15-1892-608)

Catalog No.: C15-1892-608
Mfr. No.: L9793-50MG
Mfr. Name: Sigma-Aldrich
Qty/UOM: 50
UOM: MG

Price: $1,773.80

List Price: $1,970.89

Application LP44 has been used as a 5-hydroxytryptamine (serotonin) receptor 7 (5-HT7) agonist to study its effects on mitochondria-mediated leucine-rich repeat and pyrin domain containing 3 (NLRP3) inflammasome activation. Biochem/physiol

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Description
Specifications

Application

LP44 has been used as a 5-hydroxytryptamine (serotonin) receptor 7 (5-HT7) agonist to study its effects on mitochondria-mediated leucine-rich repeat and pyrin domain containing 3 (NLRP3) inflammasome activation.

Biochem/physiol Actions

LP44 is a high affinity 5-HT₇ receptor agonist. K_i = 0.22 nM. LP44 displays selectivity over 5-HT_1A and 5-HT_2A receptors (200- and >1000-fold, respectively). LP44 induces relaxation of substance P-stimulated guinea pig ileum (EC₅₀ = 2.56 μM).

UPC:: 51183706
Condition:: New
Availability:: 3-5 Days
Weight:: 1.00 Ounces
HazmatClass:: No
MPN:: L9793-50MG
CAS:: 824958-12-5

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