LY293111 is a potent antagonist of leukotrine B4 repector (BLT|1|) which inhibits the specific binding of radiolabeled-LTB|4|to this receptor (IC|50|= 17.6 nM). This further prevents LTB|4|-induced chemotaxis of neutrophils (IC|50|= 6.3 nM). Additional|in vitro|studies have shown that LY293111 inhibits growth of MiaPaCa-2 and AsPC-1 cell lines and subcutaneous xenografts by inducing apoptosis and S-phase arrest.
Specifictaions: Moligand™, 10mM in DMSO
MDL Number: C33H33FO6
Molecular Formula: 544.6
PubChem CID: 177941
Isomeric SMILES: CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/L339608-SCI_2814eb71d55936e32acb1fa69c78aa6c.pdf
- UPC:
- 41104704
- Condition:
- New
- Availability:
- 5-10 days
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- L339608-1ml
- CAS:
- 161172-51-6
- Product Size:
- 1ml
- Physical Hazards:
- Flammable Liquid