General description
MabSelect™ Xtra, with extra high dynamic binding capacity, is a member of the MabSelect™ family. Developed to meet the demands of increasing levels of expression in monoclonal antibody feedstocks.
Application
MabSelect™ Xtra has the same recombinant Protein A ligand as MabSelect™ but is based on a high-fLow Agarose base matrix with increased porosity and a slightly decreased particle size compared to MabSelect. This results in higher capacity—MabSelect™ Xtra has about 30% higher dynamic binding capacity for IgG than currently available Protein A chromatography media. In addition, MabSelect™ Xtra has a higher capacitiy for many Fc-fusion Proteins.
The medium provides a lower overall production cost due to the possibility of processing concentrated feedstocks in fewer batches.
MabSelect™ Xtra is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, MabSelect™ Xtra meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
- Higher dynamic binding capacity than currently available Protein A chromatography media.
- Improved process economics through reduced raw materials costs and/or reduced number of cycles
- High purity capture due to high ligand selectivity and matrix hydrophilicity
- Slightly lower pressure/fLow properties compared to MabSelect™ SuRe™ and MabSelect
Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Legal Information
MabSelect is a trademark of Cytiva
SuRe is a trademark of Cytiva
- UPC:
- 51442710
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- GE17-5269-02
