Polyethylene Glycol (PEGs & PEOs)

4-bromobutylphosphonic acid contains a bromine group and a phosphonic acid group. The bromine is a good leaving group. The hydrophilic properties of the PEG linkers increase the water solubility of the compound in aqueous media.

4-Fluoro-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).

4-Fluoro-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).

4arm-Carboxy-Amido-PEG, MW 20K is a branched PEG derivative with four terminal carboxylic acids. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

4arm-Carboxy-Amido-PEG, MW 10K is a branched PEG derivative with four terminal carboxylic acids. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

4arm-Carboxy-Amido-PEG, MW 10K is a branched PEG derivative with four terminal carboxylic acids. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

4arm-Carboxy-Amido-PEG, MW 10K is a branched PEG derivative with four terminal carboxylic acids. The terminal carboxylic acids can be reacted with primary amino groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

4arm-PEG-ACRL, MW 10K is a branched PEG derivative with four terminal acrylate groups. The acrylate groups enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.

4arm-PEG-ACRL, MW 10K is a branched PEG derivative with four terminal acrylate groups. The acrylate groups enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.

4arm-PEG-ACRL, MW 10K is a branched PEG derivative with four terminal acrylate groups. The acrylate groups enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.

4arm-PEG-ACRL, MW 20K is a branched PEG derivative with four terminal acrylate groups. The acrylate groups enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.

4arm-PEG-ACRL, MW 20K is a branched PEG derivative with four terminal acrylate groups. The acrylate groups enables Michael addition. The hydrophilic PEG spacer increases solubility in aqueous media.