Polyethylene Glycol (PEGs & PEOs)

BCN-PEG3-Val-Cit is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The hydrophilic PEG spacer increases solubility

BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged

BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged

BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged

BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged

Benzyl-PEG2-amine is a PEG derivative which contains a benzyl protecting group and a free amine. Benzyl groups can be used as alcohol protecting groups and can be removed via hydrogenolysis. The primary amine can react with carboxylic acids,

Benzyl-PEG2-amine is a PEG derivative which contains a benzyl protecting group and a free amine. Benzyl groups can be used as alcohol protecting groups and can be removed via hydrogenolysis. The primary amine can react with carboxylic acids,

Benzyl-PEG2-amine is a PEG derivative which contains a benzyl protecting group and a free amine. Benzyl groups can be used as alcohol protecting groups and can be removed via hydrogenolysis. The primary amine can react with carboxylic acids,

Benzyl-PEG2-azide is a PEG derivative with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water

Benzyl-PEG2-azide is a PEG derivative with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water

Benzyl-PEG2-azide is a PEG derivative with an acid labile, benzyl protecting group. The azide can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties. The hydrophilic PEG linker increases the water

Benzyl-PEG2-CH2CO2tBu is a PEG derivative containing a benzyl group and a t-butyl protected carbonyl. Both the benzyl and t-Butyl group can be removed under acidic conditions. The carboxylic acid can be reacted with primary amines in the presence of