Name: MB-3 >=95% (HPLC) (C005B-454514)
SKU: C005B-454514
Price: 421.56 USD
Availability: InStock

MB-3 >=95% (HPLC) (C005B-454514)

Catalog No.

C005B-454514

Mfr. No.

M2449-5MG

Mfr. Name

Sigma-Aldrich

Qty/UOM

UOM

Price: $421.56

List Price: $468.40

Application MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor: to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylations to analyze its effects on the growth of Arabidopsis thaliana

Enjoy exclusive benefits including discounted pricing on orders by contacting our Sales Executives to open an account. Contact Us

Description
Specifications

Application

MB-3 has been used as a general control non-repressible 5 (GCN5) inhibitor:

to study its effects on lamin A/C-associated pY19-Cav-2-mediated histone H3 acetylations
to analyze its effects on the growth of Arabidopsis thaliana seedlings
to study its effects on craniofacial chondrocyte maturation

Biochem/physiol Actions

MB-3 can modify the gene expression in murine embryonic stem cells as well as yeast. It hinders the acetyltransferase activity of general control non-repressible 5 (GCN5) by binding to acetyl CoA pocket present in GCN5.

MB-3 is a Gcn5 HAT (Histone Acetyltransferase) inhibitor; anti-inflammatory, anti-carcinogenic.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.