Product Describtion:MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively.InformationMBQ-167 MBQ-167 is a potent and dual inhibitor of Rac and Cdc42 with IC50s of 103 nM and 78 nM respectively, in metastatic breast cancer cells.Targetscdc42 (in metastatic breast cancer cells); Rac (in metastatic breast cancer cells) 78 nM; 103 nMIn vitroMBQ-167 inhibits mammary tumor growth and metastasis in immunocompromised mice by ~90%.Cell Research(from reference)Cell lines：MDA-MB-231 cells Concentrations：250 or 500 nM Incubation Time：24 h. Specifications and Purity: 98%. Molecular Formula: C22H18N4. Molecular Weight: 338.41. PubChem CID: 129896932. Isomeric SMILES: CCN1C2=C(C=C(C=C2)N3C(=CN=N3)C4=CC=CC=C4)C5=CC=CC=C51.
- UPC:
- 12352005
- Condition:
- New
- Availability:
- 1 day
- Weight:
- 1.06 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M414152-50mg
- CAS:
- 2097938-73-1
- Product Size:
- 50mg
