General description
Mca NovaTag resin is an ideal tool for the synthesis of FRET peptide substrates based on the 7-methoxycoumarin (Mca) and 2,4-dinitrophenyl(Dnp) fluorophore/quench pair. The resin pre-loaded with the Mca fluorophore can be used directly in Fmoc SPPS. Following peptide assembly, the Dnp group can be introduced using Fmoc-Lys(Dnp)-OH, to give after TFA cleavage the desired FRET peptide substrate.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Linkage
Replaces: 04-12-3902
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.20 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Quality Level: 200. product line: NovaSyn®. TG, Novabiochem®. . form: beads. reaction suitability: reaction type: Fmoc solid-phase peptide synthesis. manufacturer/tradename: Novabiochem®. . application(s): peptide synthesis. functional group: amine. storage temp.: 15-25°C. Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable.- UPC:
- 51461535
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 8550528100