General description
A free radical scavenger and antioxidant that reduces post-ischemic brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.
A free radical scavenger and antioxidant that reduces post-ischemie brain injury. Inhibits iron-dependent peroxidation in rat brain homogenates (IC50 = 15 µM). Inhibits mitochondrial permeability transition pore.
Biochem/physiol Actions
Cell permeable: no
Primary Target
A free radical scavenger and antioxidant
Product does not compete with ATP.
Reversible: no
Target IC50: 15 µM inhibiting iron-dependent peroxidation in rat brain homogenates
Packaging
Packaged under inert gas
Warning
Toxicity: Harmful (C)
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Katare, R. G., et al. 2003. Am. J. Physiol.285, H2171.
Kawai, H., et al. 1997. J. Pharmacol. Exp. Ther. 281, 921.
Yamamoto, Y., et al. 1996. Redox. Report 2, 333.
Watanabe, T., et al. 1994. J. Pharmacol. Exp. Ther. 268, 1597.
Nishi, H., et al. 1989. Stroke 20, 1236.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 41141931
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 443300-500MG
