InformationME-401 (PWT-143, P110δ-IN-1) is an oral, potent and selective inhibitor ofPhosphatidylinositol 3-Kinase (PI3K) P110δwith IC50 of 0.6 nM in cellular assay.TargetsP110δ (Cell-free assay) 0.6 nMIn vivoME-401 is an oral, once-daily, selective PI3Kδ inhibitor with an optimized pharmacologic profile that is in clinical development for the treatment of B-cell malignancies. ME-401 can be orally absorbed, distribute to target tissues, enter and accumulate in target cells, and bind to the target with high affinity to exert its mechanism of action. Specification: 0.98 Molecular Formula: C31H40N8O3S Molecular Weight: 604.77 PubChem CID: 73441802 Isomeric SMILES: CC(C)(CC1=CC=CC=C1C2CCN(CC2)C)NC3=NC(=NC(=N3)N4CCOCC4)N5C6=CC=CC=C6N=C5S(=O)(=O)C Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M414266-SCI_21251d427a545c93b2077040e66d0b60.pdf
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 2 weeks
- Weight:
- 0.97 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M414266-50mg
- CAS:
- 1595129-71-7
- Product Size:
- 50mg
