A noncompetitive nicotinic acetylcholine receptor antagonist with preferential activity at the &alpha3&beta4 subtype (IC50 = 90-640 nM) compared to &alpha4&beta2, &alpha3&beta2, and &alpha7 subtypes (IC50s range from 1-7
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A noncompetitive nicotinic acetylcholine receptor antagonist with preferential activity at the α3β4 subtype (IC50 = 90-640 nM) compared to α4β2, α3β2, and α7 subtypes (IC50s range from 1-7 μM).
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