Combination antimalarials

InformationDDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

InformationDDD107498 DDD107498 (M-5717, DDD-498) is a P. falciparum translation elongation factor 2 inhibitor. DDD107498 exhibits a potent and novel spectrum of antimalarial activity against multiple life-cycle stages of the Plasmodium parasite.

Demethyl Curcumin is a metabolite of Curcumin with potent activity against Trypanosoma and Leishmania species.

Demethyl Curcumin is a metabolite of Curcumin with potent activity against Trypanosoma and Leishmania species.

Demethyl Curcumin is a metabolite of Curcumin with potent activity against Trypanosoma and Leishmania species.

A secondary metabolite produced by some species of lichen that binds FAS-II enzymes to produce antibacterial and antiplasmodial effects inhibits PfFabZ and PfFabI (IC₅₀ = 10.7 and 36.

Febrifugine is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga , with antimalarial activityForm:SolidIC50&amp: Target:Plasmodium.

Biochem/physiol Actions Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum , the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver

Biochem/physiol Actions Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum , the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver

General description Flocoumafen is a second generation anticoagulant rodenticides , which can have an array of applications in pest control.(1) It belongs to the 4-hydroxycoumarin class of rodenticides.

Ganaplacide (KAF156) hydrochloride is a first-in-class, orally active imidazolopiperazine antimalarial agent. Ganaplacide hydrochloride is active against a broad range of Plasmodium species, including drug-resistant parasites. Ganaplacide

Ganaplacide (KAF156) hydrochloride is a first-in-class, orally active imidazolopiperazine antimalarial agent. Ganaplacide hydrochloride is active against a broad range of Plasmodium species, including drug-resistant parasites. Ganaplacide