Distamycin a or stallimycin

A selective, potent, and cell-permeable inhibitor of mTOR (IC₅₀ = 4.3 nM) which blocks signaling through both mTORC1 and mTORC2 induces G1 cell cycle arrest in both rapamycin-sensitive and rapamycin-resistant cancer cell lines and

A selective, potent, and cell-permeable inhibitor of mTOR (IC₅₀ = 4.3 nM) which blocks signaling through both mTORC1 and mTORC2 induces G1 cell cycle arrest in both rapamycin-sensitive and rapamycin-resistant cancer cell lines and