Antidepressant bicyclo compounds and carbolines

(-)-Bilobalide from Ginkgo biloba leaves.

(-)-Bilobalide from Ginkgo biloba leaves.

Bilobalide is a biologically active terpenic trilactone (terpenoid) extracted from Ginkgo biloba . It is synthesized from geranylgeranyl pyrophosphate (GGPP).

(1S 5S)-SPIRO[BICYCLO[3.2.

ApplicationReactant for: Preparation of disubstituted tetrahydrofurans as selective serotonin re-uptake inhibitors for the treatment of depression Ring-opening reactions with Wittig reagents Enantioselective total synthesis of the phytotoxic lactone

Takasago Ligands and Complexes for Asymmetric Reactions.

(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a cannabinoid receptor type 1 (CB 1 R)/iNOS antagonist, with a K i of 5.7 nM for CB 1 R. (Rac)-Zevaquenabant is potential for the research of liver fibrosisIC50&amp: Target:CB 1 R/iNOS.

(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y

(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y

Application：Catalyst in rhodium-N-heterocyclic carbene complex-catalyzed O-arylation of phenols with arylbromides； Reactant in preparation of Pd-PEPPSI complexes for catalysis of cross-coupling reactions；.

Application：Catalyst in rhodium-N-heterocyclic carbene complex-catalyzed O-arylation of phenols with arylbromides； Reactant in preparation of Pd-PEPPSI complexes for catalysis of cross-coupling reactions；.

Application：Catalyst in rhodium-N-heterocyclic carbene complex-catalyzed O-arylation of phenols with arylbromides； Reactant in preparation of Pd-PEPPSI complexes for catalysis of cross-coupling reactions；.