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WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM: does not inhibit ERBB2 phosphorylation (T798I).A mutant EGFR phosphorylation inhibitor.

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM: does not inhibit ERBB2 phosphorylation (T798I).A mutant EGFR phosphorylation inhibitor.

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM: does not inhibit ERBB2 phosphorylation (T798I).A mutant EGFR phosphorylation inhibitor.

WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM: does not inhibit ERBB2 phosphorylation (T798I).A mutant EGFR phosphorylation inhibitor.