Sertraline hydrochloride

A monoamine neurotransmitter produced in serotonergic neurons in the CNS and in enterochromaffin cells in the gastrointestinal tract that is important in the regulation of mood, sleep, vomiting, sexuality, and appetite.

A monoamine neurotransmitter produced in serotonergic neurons in the CNS and in enterochromaffin cells in the gastrointestinal tract that is important in the regulation of mood, sleep, vomiting, sexuality, and appetite.

SERT-IN-2 is a potent SERT inhibitor ( IC 50 =0.58 nM) with promising anti-depression efficacy. SERT-IN-2 shows good bioavailability of 83.28% in rats. SERT-IN-2 can cross the blood-brain barrierIn VivoSERT-IN-2 (DH4) (2.5 mg/kg, 5 mg/kg: p.o.:

SERT-IN-2 is a potent SERT inhibitor ( IC 50 =0.58 nM) with promising anti-depression efficacy. SERT-IN-2 shows good bioavailability of 83.28% in rats. SERT-IN-2 can cross the blood-brain barrierIn VivoSERT-IN-2 (DH4) (2.5 mg/kg, 5 mg/kg: p.o.:

SERT-IN-2 is a potent SERT inhibitor ( IC 50 =0.58 nM) with promising anti-depression efficacy. SERT-IN-2 shows good bioavailability of 83.28% in rats. SERT-IN-2 can cross the blood-brain barrierIn VivoSERT-IN-2 (DH4) (2.5 mg/kg, 5 mg/kg: p.o.:

A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC₅₀s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively).

A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC₅₀s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively).

A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC₅₀s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively).

A tetraline that inhibits monoamine transporters with selectivity for the serotonin transporter (IC₅₀s = 70, 520, and 720 nM for the serotonin, dopamine, and norepinephrine transporters, respectively).

Sertraline Carbamoyl Glucuronide is the major metabolite of the anti-depressant Sertraline.

General description Sertraline hydrochloride is a SSRI i.e selective serotonin reuptake inhibitor.

General description Sertraline hydrochloride is a SSRI i.e selective serotonin reuptake inhibitor.