Antifungals, synthesized

Application Reactant for preparation of: Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity Boron-containing benzoxaboroles as antimalarial agents Methyl alkenyl quinolones as antimycobacterial agents Solandelactone

Application Reactant for preparation of: Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity Boron-containing benzoxaboroles as antimalarial agents Methyl alkenyl quinolones as antimycobacterial agents Solandelactone

application：Reactant for the synthesis of:β-amyloid plaque ligandsSelective norbornane-type aspartate analog inhibitors of glutamate transporter 1Pyrethroids with insecticidal activityChlorinated aromatic avenaciolide analogs with antifungal

Application (4 S )-(+)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane may be used in the preparation (prop-2-ynyloxy)ethyl-tethered dioxolanes via O -propargylation. It may also be used as an intermediate in the total synthesis of rugulactone.

Application (4 S )-(+)-4-(2-Hydroxyethyl)-2,2-dimethyl-1,3-dioxolane may be used in the preparation (prop-2-ynyloxy)ethyl-tethered dioxolanes via O -propargylation. It may also be used as an intermediate in the total synthesis of rugulactone.

A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC 50 = 8 nM) in an ATP-competitive and irreversible manner, while inhibiting MEK1 (IC 50 = 411 nM)

Application ( R )-(-)-3-Hydroxytetrahydrofuran may be used as building block in the synthesis of potent HIV protease inhibitors.

Application ( S )-( &#8722 )-1,2-Epoxybutane can be used: As a starting material to prepare (+)- and (&#8722)-homononactic acids, which are used as intermediates in the total synthesis of a cyclic antibiotic tetranactin. To prepare a chiral

Used to prepare a novel class of antifungal agents.

Used to prepare a novel class of antifungal agents.

Used to prepare a novel class of antifungal agents.

(S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity.In VitroThe natural racemic Gossypol has two enantiomers, namely the (-)-Gossypol and (S)-Gossypol