Atorvastatin lactone

Cholesterol, a major sterol is the precursor for steroid hormones, bile acid and vitamin in mammals and coordinates endocytosis. It complexes with protein to form lipoproteins for transport in blood.

A natural flavonoid that has potent antioxidant and anti-inflammatory properties acts as an antagonist of AhR, inducing apoptosis in cancer cells also inhibits CYP1A1 with an IC₅₀ value of less than 1 &microM.

Biochem/physiol Actions Hymeglusin is a specific &#946: lactone inhibitor of eukaryotic hydroxymethylglutaryl-CoA synthase (HMGCS), a key enzyme in the cholesterol biosynthetic pathway. Unlike other fungal metabolites, Hymeglusin inhibits

Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates

Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates

Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates

General description Inulicin, a sesquiterpene lactone, is a natural bioactive compound commonly sourced from plants like Pentanema britannicum and Inula japonica . Current research indicates that this plant-derived metabolite may possess

A potent in vitro inhibitor of sn-1 DAGL&alpha (IC₅₀ = 18 nM) blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGL&alpha, with a Ki value of 0.7 &microM inhibits the hydrolysis of 2-AG by the monoacylglycerol

A potent in vitro inhibitor of sn-1 DAGL&alpha (IC₅₀ = 18 nM) blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGL&alpha, with a Ki value of 0.7 &microM inhibits the hydrolysis of 2-AG by the monoacylglycerol

A potent in vitro inhibitor of sn-1 DAGL&alpha (IC₅₀ = 18 nM) blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGL&alpha, with a Ki value of 0.7 &microM inhibits the hydrolysis of 2-AG by the monoacylglycerol

A potent in vitro inhibitor of sn-1 DAGL&alpha (IC₅₀ = 18 nM) blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural substrate of DAGL&alpha, with a Ki value of 0.7 &microM inhibits the hydrolysis of 2-AG by the monoacylglycerol

A Simvastatin intermediate and Lovastatin analog that has the activities of decreasing blood cholesterol and low-d. lipoprotein. It can be used to preparation hypolipidemic medicine.