Antihypertensive drugs

A cell-permeable Akti-1/2- (sc-202048) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC|50|= 805 nM for Akt2, &gt:10 µM for Akt1/3, and &gt:50

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

Amino Acid Sequence Ala-Tyr-Pro-Gly-Lys-Phe-NH2 General description Ala-Tyr-Pro-Gly-Lys-Phe-NH 2 (AYPGKF- NH 2 ) is a selective, specific proteinase-activated receptor 4 (PAR4) agonist peptide. PAR4 is a G-protein-coupled receptor that is expressed

Used as wrapping for fractures where single layers conform to shape of limb or body-elasticity allows for swelling without discomfort. Dressing for vein ligations, plastic surgery procedures and with burn dressings.