Antihypertensive drugs

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM.

InformationAliskiren hemifumarate is a directrenininhibitor withIC50of 1.5 nM.In vitroAliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site

Biochem/physiol Actions Aliskiren hemifumarate (ALS) has been used to treat hypertension, alone or with other antihypertensive medications. It is suitable for oral administration.

Biochem/physiol Actions Aliskiren hemifumarate (ALS) has been used to treat hypertension, alone or with other antihypertensive medications. It is suitable for oral administration.

Aliskiren hydrochloride is a direct renin inhibitor with an IC|50|= 0.72 nM. Renin is the first enzyme in the renin-angiotensin-aldosterone system (RAAS) and cleaves angiotensinogen, an inactive peptide, into angiotensin I. Inhibition of renin

A selective inhibitor of the TGF-&beta type 1 receptor ALK5 (IC₅₀s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-&beta cellular assay, and ALK5 binding in HepG2 cells, respectively) used to induce stem cell pluripotency by

General description This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate.

Allihn Reflux Condenser with a water cooled inner drip tip at the bottom for Soxhlet Extractors. Joint Size: Available in 34/45, 45/50, and 55/50 Jacket Length: Available in 190, 260, and 300mm.

Allihn Reflux Condenser with a water cooled inner drip tip at the bottom for Soxhlet Extractors. Joint Size: Available in 34/45, 45/50, and 55/50 Jacket Length: Available in 190, 260, and 300mm.