Antihypertensive drugs

AHU-377 is an inhibitor of neprilysin with IC50 value of 5 nM. AHU-377 and the angiotensin II AT1 receptor antagonist valsartan compose LCZ696 in a 1:1 molar ratio. LCZ696 is an angiotensin receptor neprilysin inhibitor. It can reduce blood pressure

A cell-permeable and reversible version of the Akt Inhibitor VI, Akt-in (Cat. No.

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

Akt1/Akt2-IN-1 (Compound 17) is an allosteric inhibitor of Akt1 ( IC 50 =3.5 nM) and Akt2 (IC 50 =42 nM), with potent and balanced activityIn VitroConsistent with the allosteric mode of inhibition, Akt1/Akt2-IN-1 (Compound 17) is dependent on the

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

The isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist (Ki = 3.2 &microM, EC50 = 0.80 &microM) produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 &microg dose given twice daily.

Amino Acid Sequence Ala-Tyr-Pro-Gly-Lys-Phe-NH2 General description Ala-Tyr-Pro-Gly-Lys-Phe-NH 2 (AYPGKF- NH 2 ) is a selective, specific proteinase-activated receptor 4 (PAR4) agonist peptide. PAR4 is a G-protein-coupled receptor that is expressed