Antihypertensive drugs

Endogenous ligand of the APJ receptor, with an EC50 of 0.37 nM acts primarily in the periphery and CNS, playing important roles in regulating cardiovascular function, fluid homeostasis, hypertension, and insulin sensitivity.

Full-length mature apelin peptide acts primarily in the regulation of cardiovascular function, fluid homeostasis, hypertension, and insulin sensitivity a less potent APJ agonist than either apelin-17 or apelin-13 (EC50 = 20, 2.5, and 0.

Apilimod

Apilimod

Biochem/physiol Actions Apixaban is an orally active, active site-targeting, highly potent and selective factor Xa (FXa) inhibitor (human/rabbit Ki = 0.08/0.

Biochem/physiol Actions Apixaban is an orally active, active site-targeting, highly potent and selective factor Xa (FXa) inhibitor (human/rabbit Ki = 0.08/0.

An orally available, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM) effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

An orally available, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM) effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

An orally available, selective inhibitor of both free and prothrombinase-bound factor Xa (Ki = 0.8 nM) effective anticoagulant in both preclinical and clinical models of venous and arterial thrombosis.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the

Aprepitant

Aprepitant