Efonidipine

A urinary metabolite of (&plusmn)14(15)-EET which is elevated in pregnancy-induced hypertension.

A urinary metabolite of (&plusmn)14(15)-EET which is elevated in pregnancy-induced hypertension.

A urinary metabolite of (&plusmn)14(15)-EET which is elevated in pregnancy-induced hypertension.

Biochem/physiol Actions Racemic efonidipine has both L-type and T-type calcium channel blocking activity. The R(&#8722)-isomer appears to be very selective for T-type calcium channel.

Biochem/physiol Actions Racemic efonidipine has both L-type and T-type calcium channel blocking activity. The R(&#8722)-isomer appears to be very selective for T-type calcium channel.

InformationLenvatinib (E7080) is a multi-target inhibitor, mostly forVEGFR2(KDR)/VEGFR3(Flt-4)withIC50of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/β in cell-free assays. Lenvatinib

EGFR/ErbB1 Selective Inhibitors | Activators.

EGFR/ErbB1 Selective Inhibitors | Activators.

EGFR/ErbB1 Selective Inhibitors | Activators.

Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR , such as L858R EGFR , Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitor More