Guanfacine hydrochloride

Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect.

Guanfacine-13C, 15N3 is a centrally acting α-adrenoceptor agonist. Antihypertensive.

An endogenous homolog of arachidonyl glycine that inhibits AEA hydrolysis in FAAH-containing N18TG2 cell membranes with an IC₅₀ value of 25 &microM.

An endogenous homolog of arachidonyl glycine that inhibits AEA hydrolysis in FAAH-containing N18TG2 cell membranes with an IC₅₀ value of 25 &microM.

An endogenous homolog of arachidonyl glycine that inhibits AEA hydrolysis in FAAH-containing N18TG2 cell membranes with an IC₅₀ value of 25 &microM.

General description This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled

Biochem/physiol Actions MU1210 is a potent and selective inhibitor against cdc-like kinase (cdc2-like kinase) CLK1, CLK2, CLK4 (CLK1/2/4 IC 50 = 8/20/12 nM: CLK1/2/4 K i = 84/91/23 nM by NanoBRET) and HIPK2 (IC 50 = 29 nM) with good selectivity

Biochem/physiol Actions MU1210 is a potent and selective inhibitor against cdc-like kinase (cdc2-like kinase) CLK1, CLK2, CLK4 (CLK1/2/4 IC 50 = 8/20/12 nM: CLK1/2/4 K i = 84/91/23 nM by NanoBRET) and HIPK2 (IC 50 = 29 nM) with good selectivity