Ambazone

Selectively inhibits ALK1 (IC₅₀ = 46 nM) and ALK2 (IC₅₀ = 32 nM) with &gt300-fold selectivity over ALK3, ALK6, and VEGF type 2 receptor inhibits BMP4 signaling with an IC₅₀ value of 152 nM in a functional assay.

Selectively inhibits ALK1 (IC₅₀ = 46 nM) and ALK2 (IC₅₀ = 32 nM) with &gt300-fold selectivity over ALK3, ALK6, and VEGF type 2 receptor inhibits BMP4 signaling with an IC₅₀ value of 152 nM in a functional assay.

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC 50 value of &lt:10 nM.Form:Solid.

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC 50 value of &lt:10 nM.Form:Solid.

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC 50 value of &lt:10 nM.Form:Solid.

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC 50 value of &lt:10 nM.Form:Solid.

MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC 50 value of &lt:10 nM.

A cell-permeable biphenylsulfonamido-hydroxamate compound that acts a potent and Zn 2+ -binding site-targeting inhibitor of MMP-2 (IC 50 = 12 nM). It exhibits good selectivity over MMP-9 and MMP-3 (IC 50 = 0.

A cell-permeable, potent inhibitor of human MMP-3 (stromelysin K i = 130 nM). A potent and cell-permeable inhibitor of human MMP-3 (K i = 130 nM).

General description Recombinant, human pro-MMP-9 expressed in CHO cells. A portion (less than 10%) of the enzyme may be seen as a naturally-occurring dimer.

InformationMobocertinib (TAK788, AP32788), an investigational TKI, is a potent, selective preclinical inhibitor ofepidermal growth factor receptor (EGFR)andHER2mutations. Mobocertinib (TAK788) is an antineoplastic agent.TargetsEGFR : HER2.

General description Monoclonal Anti-CYBA (mouse IgM isotype) is derived from the hybridoma CB-64 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a sequence at the