Cemadotin

InformationCediranib (AZD2171, NSC-732208) is a highly potentVEGFR(KDR)inhibitor withIC50of &lt:1 nM, also inhibits Flt1/4 withIC50of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and &gt:1000-fold selective more for VEGFR

Biochem/physiol Actions Cediranib (AZD2171) is an orally active anticancer agent and a highly potent ATP-competitive receptor tyrosine kinase (RTK) inhibitor against VEGFR (IC 50 = 5 nM/Flt-1 (VEGFR1), &lt:1 nM/KDR (VEGFR2), &#8804:3 nM/Flt-4

Biochem/physiol Actions Cediranib (AZD2171) is an orally active anticancer agent and a highly potent ATP-competitive receptor tyrosine kinase (RTK) inhibitor against VEGFR (IC 50 = 5 nM/Flt-1 (VEGFR1), &lt:1 nM/KDR (VEGFR2), &#8804:3 nM/Flt-4

Cedirogant (ABBV-157) is an orally active RORγt inverse agonist. Cedirogant can be used for psoriasis researchIn VitroThe transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17

Biochem/physiol Actions Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal

Biochem/physiol Actions Ceefourin 1 is a potent and highly selective MRP4 (Multidrug resistance protein 4) inhibitor that exhibits low cellular toxicity and high microsomal and acid stability. Ceefourin 1 inhibits PDAC (pancreatic ductal

Celastrol, Celastrus scandens, a compound originally purified from Tripterygium wilfordii, has been shown to be an anti-peroxidative and anti-angiogenic agent. Mechanistic studies suggest that Celastrol suppresses levels of VEGF and Flk-1 receptors,

Celastrol, Celastrus scandens, a compound originally purified from Tripterygium wilfordii, has been shown to be an anti-peroxidative and anti-angiogenic agent. Mechanistic studies suggest that Celastrol suppresses levels of VEGF and Flk-1 receptors,

Celosin L is a triterpenoid saponin with hepaprotective activity. Celosin L exhibits protective effects against APAP-induced hepatotoxicity in HepG2 cells.

The CEND1 antibody from Proteintech is a Rabbit Polyclonal antibody to a Recombinant Protein of human CEND1. This antibody recognizes Human,Mouse,Rat antigen.

A potent inhibitor of ALK (IC₅₀ = 1.9 nM) that induces concentration-dependent growth inhibition or cytotoxicity of ALK-positive cancer cells inhibits ALK tyrosine phosphorylation in tumor xenografts in mice for more than 12 hours

Cerberin is a cardiac glycoside that has been found in C. odollam and has cytotoxic and cardiac modulatory activities. It is cytotoxic to KB and NCI H187 cancer cells ( IC 50 s=1.92 and 1.24 μg/mL).1 Cerberin inhibits Na+/K+-ATPase, increasing