Cemadotin

A potent inhibitor of hedgehog-induced cellular activity (IC₅₀ = 100-200 nM) binds directly with the pathway activator Smo (Ki = 44 nM) blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of

CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell

CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell

DCLK1-IN-1 is a selective, in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1) domain that binds to DCLK1 and DCLK2 with IC50 of 9.5 nM and 31 nM, respectively. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases with IC50 of 57.2 nM

DCLK1-IN-1 is a selective, in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1) domain that binds to DCLK1 and DCLK2 with IC50 of 9.5 nM and 31 nM, respectively. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases with IC50 of 57.2 nM

DCLK1-IN-1 is a selective, in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1) domain that binds to DCLK1 and DCLK2 with IC50 of 9.5 nM and 31 nM, respectively. DCLK1-IN-1 inhibits DCLK1 and DCLK2 kinases with IC50 of 57.2 nM

DP-C-4 is a Cereblon -based dual PROTAC for simultaneous degradation of EGFR and PARP.Appearance:SolidIC50&amp: Target:CereblonIn Vitro:DP-C-4 (1-50 μM: 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in

Application:WB: 1/1000 – 1/10,000. Predicted molecular weight: 97.5 KDa.

Application:WB: 1/1000 – 1/10,000. Predicted molecular weight: 97.5 KDa.

Application:WB: 1/1000 – 1/10,000. Predicted molecular weight: 97.5 KDa.

Application:WB: 1/1000 – 1/10,000. Predicted molecular weight: 97.5 KDa.

MF: C23H18O4 MF: 358.37 CAS: 909-84-2