Idoxifene

A cell-permeable derivative of the D-isomer of 2-HG used to examine the contribution of D-2HG to the oxidative mitochondrial processes of IDH1-mutated cancer cells.

A cell-permeable derivative of the D-isomer of 2-HG used to examine the contribution of D-2HG to the oxidative mitochondrial processes of IDH1-mutated cancer cells.

A cell-permeable derivative of the D-isomer of 2-HG used to examine the contribution of D-2HG to the oxidative mitochondrial processes of IDH1-mutated cancer cells.

One of the main polyphenolic constituents of green tea that exhibits potent antitumor, anti-inflammatory, and antioxidant properties. Arrests cell cycling at G 0 /G 1 phase and induces apoptosis in a dose-dependent manner.

An analog of trimethoxy resveratrol inhibits the growth of a variety of human tumor cell lines at concentrations form 0.4 to 2 &microg/ml, which is 5-6 times more potent than resveratrol

3-tert-Butyl-4-hydroxyanisole is antioxidant found to inhibit chemically-induced tumor formation in animals.An antioxidant stabilizer of fats that has shown carcinogenicity at high doses.

3-tert-Butyl-4-hydroxyanisole is antioxidant found to inhibit chemically-induced tumor formation in animals.An antioxidant stabilizer of fats that has shown carcinogenicity at high doses.

3-tert-Butyl-4-hydroxyanisole is antioxidant found to inhibit chemically-induced tumor formation in animals.An antioxidant stabilizer of fats that has shown carcinogenicity at high doses.

Other Notes Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of rare and unique chemicals. Sigma-Aldrich does not collect analytical data for this product.

An IDH1 inhibitor.

An IDH1 inhibitor.

AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.AGI-5198(IDH C35) is a novel R132H-IDH1 inhibitor, identified through a high-throughput screen blocked R132H-IDH1 activity in a