Nilotinib

CDC25 Phosphatase Inhibitor I, BN82002, is a cell-permeable ortho-hydroxybenzylamino compound that has been reported to display antitumor properties. It has been shown to act as a potent, selective and irreversible inhibitor of the CDC25 phosphatase

CDC25 Phosphatase Inhibitor I, BN82002, is a cell-permeable ortho-hydroxybenzylamino compound that has been reported to display antitumor properties. It has been shown to act as a potent, selective and irreversible inhibitor of the CDC25 phosphatase

CDC25B-IN-1 (compound 4a) is a potent inhibitor of cell division cycle 25B (CDC25B) phosphatase , with a K i of 8.5 μM. CDC25B-IN-1 potently inhibits cell proliferation and colony formation, causes an increase of the G2/M phaseIC50&amp: Target:Ki:

A cell-permeable nitroindolo-guanidinohydrazone compound that acts as a potent, ATP-competitive, and highly selective Chk2 inhibitor (IC 50 = 138 and 570 nM against the phosphorylation of histone H1 by Chk2 in the presence of 10 &#181M and 1 mM of

General description A cell-permeable diamino compound that selectively blocks nuclear translocation of NF-&#954:B p65 and its transcription activity (IC 50 = 7.1 &#181:M in a NF-&#954:B reporter assay using RAW 264.

Other Notes Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of rare and unique chemicals. Sigma-Aldrich does not collect analytical data for this product.

Corning Laminin, mouse, 1mg, is used as a thin coating on tissue-culture surfaces or as a soluble additive to culture medium. Laminin is a major component of basement membranes.

Microplate Features Round well design with a solid white flat bottom. 2.

Microplate Features Round well design with a solid white flat bottom. 2.

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar

An orally available activator of mutant forms of p53 induces apoptosis in a wide variety of human tumor cells in culture, inhibits the proliferation of colorectal cancer cell lines, and is active against human glioblastoma cell lines at nanomolar