Nilotinib

I-BET567 is a potent and orally active inhibitor of pan-BET candidate with pIC 50 s of 6.9 and 7.2 for BRD4 BD1 and BD2 , respectively. I-BET567 has been demonstrated efficacy in mouse models of oncology and inflammationIn VitroI-BET567 (compound

InformationIcotinib (BPI-2009H) is a potent and specificEGFRinhibitor withIC50of 5 nM, including the EGFR, EGFR(L858R), EGFR(L861Q), EGFR(T790M) and EGFR(T790M, L858R).In vitroIcotinib inhibits EGFR activity in a dose-dependent manner, with an IC50

application：IMD-0354 has been used to study the effect of NF-κB (nuclear factor) inhibition on differentially expressed in chondrocytes 2. It has also been used to study the role of NF-κB signaling in tumor necrosis factor-induced certain

Application IMD-0354 has been used to study the effect of NF-&#954B (nuclear factor) inhibition on differentially expressed in chondrocytes 2. It has also been used to study the role of NF-&#954B signaling in tumor necrosis factor-induced certain

InformationImidazole ketone erastin (PUN30119) Imidazole ketone erastin (PUN30119, IKE) is a potent, selective, and metabolically stable system xc– inhibitor and inducer of ferroptosis .TargetsFerroptosis : system xc–In vitroImidazole ketone erastin

Immunotag™ NOB1 Antibody-Alexa Fluor® 555*

Immunotag™ NOB1 Antibody-Alexa Fluor® 555*

InformationInauhzin is a cell-permeableSIRT1inhibitor with an IC50 of 0.7-2 μM and reactivatesp53by inhibiting SIRT1 deacetylation activity.TargetsSIRT1 : p53In vitroInauhzin (INZ) is a potent p53 activator and mediates p53-dependent cytotoxicity.

InformationInauhzin is a cell-permeableSIRT1inhibitor with an IC50 of 0.7-2 μM and reactivatesp53by inhibiting SIRT1 deacetylation activity.TargetsSIRT1 : p53In vitroInauhzin (INZ) is a potent p53 activator and mediates p53-dependent cytotoxicity.

Biochem/physiol Actions INI-43 is a cell penetrant and potent inhibitor of Kpnb1-mediated nuclear import that cancer cell death via a G2–M cell cycle arrest followed by apoptosis. INI-43 inhibits the nuclear localization of Kpnb1 as well as

Biochem/physiol Actions INI-43 is a cell penetrant and potent inhibitor of Kpnb1-mediated nuclear import that cancer cell death via a G2–M cell cycle arrest followed by apoptosis. INI-43 inhibits the nuclear localization of Kpnb1 as well as

Nitrostat Tabs Unit-Dose, 0.4mg, 4x25/pk