Piritrexim

PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC 50 s of 7, 5530 and 70 nM for PIM1 , PIM2 , and PIM3 , respectively, inhibits the phosphorylation of BAD, a downstream target of PIM , with an EC 50 of 262 nM. PIM1-IN-1 shows no

Application PIM2, active, GST tagged human has been used for in vitro kinase assay in study of PIM kinases role in fms-like tyrosine kinase 3 inhibitors (FLT3i)-resistant acute myeloid leukemia. Biochem/physiol Actions PIM2 (proto-oncogene) is a

General description PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases. Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma

Biochem/physiol Actions Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential. Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as

Biochem/physiol Actions Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential. Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as

Biochem/physiol Actions Pimpinellin is a coumarin isolated from roots of Angelica dahurica and Zosima absinthifolia that exhibits anti-tumor, anti-allergic, antioxidant and anticholinesterase activities. It appears to reduce the release of

Biochem/physiol Actions Pimpinellin is a coumarin isolated from roots of Angelica dahurica and Zosima absinthifolia that exhibits anti-tumor, anti-allergic, antioxidant and anticholinesterase activities. It appears to reduce the release of

Synonym(s): Piroxicamum, Larapam Formula: C15H13N3O4S Formula weight: 331.35 CAS Number: 36322-90-4 UN Number: UN2811 Hazard Class: 6.

Synonym(s): Piroxicamum, Larapam Formula: C15H13N3O4S Formula weight: 331.35 CAS Number: 36322-90-4 UN Number: UN2811 Hazard Class: 6.

Synonym(s): Piroxicamum, Larapam Formula: C15H13N3O4S Formula weight: 331.35 CAS Number: 36322-90-4 UN Number: UN2811 Hazard Class: 6.

InformationSMI-16a is a selectivePimkinase inhibitor with IC50 values of 150 nM and 20 nM for Pim1 and Pim2 respectively.TargetsPim2 : Pim1 20 nM: 150 nM.